Iron (Fe)
Iron is a relatively abundant metal found in the sun and other stars and in meteorites. It is the fourth most abundant element in the earth's crust by weight.
Pure iron is very reactive and rapidly corrodes. It has four allotropic forms or ferrites; the alpha form is magnetic, but the magnetism disappears in the beta form. Iron is hard, brittle, fairly fusible and used to produce steel and other alloys. Common iron consists of four isotopes, and ten other isotopes are known to exist.
Iron is vital to the functions of plants and animals and carries oxygen in hemoglobin.
Medchemexpress LLC Cu-cpt-8m (TLR8-specific antagonist) | 125079-83-6 | 99.98% | 252.27 | 1 ML
CU-CPT-8m is a specific TLR8 antagonist with an IC50 of 67 nM. It reduces the proinflammatory response in TLR8-overexpressing cells without affecting TLR7 signaling at concentrations up to 75 μM. This compound inhibits R848-induced TNF-α and IL-8 mRNA levels and R848-induced TNF-α production in differentiated THP-1 monocytes.
- Specific TLR8 antagonist with an IC50 of 67 nM.
- Reduces proinflammatory response in TLR8-overexpressing cells.
- Does not affect TLR7 signaling up to 75 μM concentrations.
- Inhibits R848-induced TNF-α and IL-8 mRNA levels.
- Inhibits R848-induced TNF-α production in differentiated THP-1 monocytes with an IC50 of 90 ± 10 nM.
- Negligible cytotoxicity.
- Kd value is 220 nM.
Gold Biotechnology Inc L Glutathione Reduced 50 g
L-Glutathione is a co-substrate to glutathione transferase found in plants and animals and is involved in the elimination of free radicals resulting from both cellular respiratory and metabolic activities
FUJIFILM BIOSCIENCES INC IS CHO-CD XP - Powder
IS CHO-CD XP is an animal-component free chemically-defined growth medium designed to support excellent cell growth and production of recombinant Chinese Hamster Ovary CHO cellLines
Medchemexpress LLC AZD4694 Precursor | 1211333-20-8 | 98.8% | 443.45 | 10 MM 1 ML
AZD4694 Precursor (AZ13040214) is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques.
- Precursor for the synthesis of [18F] AZD4694.
- [18F] AZD4694 is an amyloid-β imaging ligand.
- [18F] AZD4694 exhibits high affinity for amyloid-β plaques.
- Also known as AZ13040214 and NAV4614.
Apexbio Technology LLC HyperTrap Protein G 4FF Column 5x5ml
HyperTrap Protein G 4FF Column is an affinity chromatography medium designed for the purification of immunoglobulins particularly IgG from complex biological samples The column features immobilized Protein G ligands which specifically bind to the Fc region of IgG molecules via non-covalent interactions allowing selective capture and efficient separation of antibodies This mechanism facilitates high-purity isolation of immunoglobulins without the need for harsh elution conditions The HyperTrap Protein G 4FF Column is widely utilized in biomedical research for antibody purification immunoprecipitation and preparative workflows requiring reproducible antibody isolation
Medchemexpress LLC OM-153 | 2406278-81-5 | 99.3% | C28H24FN7O2 | 1 ML
OM-153 is a potent, orally active tankyrase inhibitor targeting TNKS1/2 with high specificity. It demonstrates strong inhibitory activity against Wnt/β-catenin signaling, which is crucial for cellular proliferation, and has shown antiproliferative effects in COLO 320DM cells.
- Potently inhibits TNKS1 (IC50: 13 nM) and TNKS2 (IC50: 2 nM).
- Effectively inhibits Wnt/β-catenin signaling (IC50: 0.63 nM).
- Exhibits antiproliferative activity in COLO 320DM cells (GI50: 10 nM).
- Inhibits WNT/β-catenin, YAP, and MYC signaling pathways.
- Reduces WNT/β-catenin signaling and tumor progression in COLO 320DM xenografts.
- Potentiates anti-PD-1 immune checkpoint inhibition in melanoma models.
Gold Biotechnology Inc D Raffinose pentahydrate 500 g
Raffinose is a natural trisaccharide composed of galactose glucose and fructose It primarily serves as a carbon source for yeast as well as being an important component in some cryopreservation solutions